Bridge the Gap TO JOINT SURGERY

A MINIMALLY INVASIVE, NON-OPIOID PROCEDURE FOR CHRONIC KNEE, SHOULDER OR HIP PAIN

Download Clinical Appendix
72%

In a clinical trial comparing cooled radiofrequency ablation to a single injection of hyaluronic acid, at the 6-month timepoint, 72.4% of subject receiving CRFA reported improved GPE compared to 40.2% receiving a single injection of hyaluronic acid.

65%

Multiple clinical studies have demonstrated that >65% of subjects who received the CRFA treatment maintained ≥50% improvement in pain relief from baseline through 12 months after treatment.

91%

At 6 months, 91% of the CRFA cohort versus 24% of the IAS group reported improved global perceived effect.

* based on level 1 clinical trials comparing steroid injections and hyaluronic acid to COOLIEF* Cooled RF for chronic pain due to knee osteoarthritis

Bridging the Gap

When surgery must wait, but joint pain can't, COOLIEF* Cooled Radiofrequency (RF) can bridge the gap between short-term pain relief solutions and joint replacement surgery so patients don't have to put their lives on pause. Chronic pain patients now have a clinically proven, minimally invasive, non-opioid procedure with extended durability compared to existing treatment options.

How do Short Term Pain Relief Options Compare to Long Term Pain Relief Options for OA Knee Patients?

What are short term
pain relief options?
What are long term
pain relief options?
Is there a way to bridge the gap or avoid surgery?
Bridging the Gap static chart
Duration of Pain Relief
2 Year of Relief
1 Year of Relief
Months of Relief
Hours of Relief
Typical Treatment Algorithm for OA Knee Patients
Short-Term Pain relief Solutions
Up to 24 Months
Long-Term Pain relief Solutions
Proven to treat post TKA pain

"I am Mike Stanton. I am an anesthesiologist with a sub-specialty in interventional pain management. I have severe degenerative joint disease. I am a candidate for a left knee replacement, but I’ve tried to put that off as long as I can, and that’s why I elected to have the COOLIEF* procedure. I honestly did not get the outcome that I expected. My pain was over. I had no pain, no pain. It was very freeing and very exciting."
Individual results may vary.

Dr. J. Mike Stanton Dallas, TX - Anesthesiologist and COOLIEF* patient

What is Cooled RF AblAtion?

A COOLIEF* RF generator produces radiofrequency energy that emanates from the probe tip, heating tissues through ionic heating.

COOLIEF* Cooled RF probes produce 5x larger, spherical lesions compared to standard radiofrequency probes. Larger lesions can help overcome nerve variability.

Internal cooled probes manage temperature at the tissue-tip interface, prevent charring, and enable the delivery of 3.7x more energy than standard radiofrequency probes.

See how COOLIEF* Cooled RF works

Hear from your peers

8:52

Chapter 1: Introduction and Overview

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10:52

Chapter 2: Treating the Non-Operative Knee OA Patient

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14:00

Chapter 3: CRFA Compared to HA: 6 Month Data

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27:00

Chapter 4: CRFA Compared to HA: 12 Month Data

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32:00

Chapter 5: Summary of Clinical Effectiveness of CRFA

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35:00

Chapter 6: Q & A

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Frequently Asked Questions

Do you offer training help?
COOLIEF* Cooled RF has a highly trained and experienced sales and clinical team. To find an Avanos representative in your area, please visit avanospainmanagement.com/contact-a-sales-rep.
Is a diagnostic nerve block necessary before treatment with COOLIEF* Cooled RF?
A diagnostic nerve block is necessary before treatment with COOLIEF* Cooled RF
How does COOLIEF* Cooled RF work?
COOLIEF* Cooled RF is the first minimally-invasive, non-opioid thermal radiofrequency pain management system that uses internally cooled probes to safely deactivate pain-causing sensory nerves.
What areas of the body can COOLIEF* Cooled RF be used in?
COOLIEF* Cooled RF can be used in the knee, hip, shoulder and spine.
Are there results that show longer than 12 months of pain relief with COOLIEF* Cooled RF?
Clinical trials have demonstrated the extended clinical durability of COOLIEF*. The majority of subjects experienced pain relief lasting 12 months, with some experiencing pain relief lasting upwards of 24 months.
Can the COOLIEF* Cooled RF procedure be done again?
The COOLIEF* Cooled RF procedure can be repeated at 6 months if needed.
Can the COOLIEF* Cooled RF procedure be done via ultrasound?
The Avanos sales and clinical team can train healthcare professionals on the COOLIEF* Cooled RF ultrasound knee technique.
See how COOLIEF* Cooled RF can fit into your treatment algorithm for patients with:
Chronic knee pain
Chronic knee pain
Chronic shoulder pain
Chronic shoulder pain
Chronic hip pain
Chronic hip pain

download the Clinical Appendix

OR contact a representative in your area.

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The Clinical Appendix consists of a literature summary surrounding the use of cooled radiofrequency ablation for the treatment of chronic joint pain. The study summaries are:

  • Published in peer-reviewed journals
  • Randomized controlled, retrospective comparison, case series; and review papers (systematic/meta-analysis)
  • Related to the use and/or anatomical considerations of cooled radiofrequency ablation